1800History
Written accounts and archaeological finds show that Native Americans inhabited the Creve Coeur area from 9500 BC to 1800 AD.
1803History
When the area was acquired by the United States through the Louisiana Purchase in 1803, the Lewis and Clark Expedition came through Creve Coeur.
1949Government
Creve Coeur was incorporated in 1949.
1976Government
== Government ==
The City of Creve Coeur's Charter was adopted in 1976, providing for a council-city administrator form of government.
2000History
=== 2000 census ===
As of the census of 2000, 16,500 people, 6,988 households, and 4,465 families were living in the city.
2006Culture
Isle of Capri Casinos moved its headquarters to Creve Coeur from Biloxi, Mississippi, in 2006.
2010History
=== 2010 census ===
As of the census of 2010, 17,833 people, 7,654 households, and 4,717 families were living in the city.
2011History
=== Top 10 employers ===
According to the city's 2011 Comprehensive Annual Financial the top employers in the city are:
=== Notable businesses ===
According to St.
2012History
Louis Business Journal Book of Lists 2012, Creve Coeur is home to several leading businesses in the St.
2016History
The 2016-2020 5-year American Community Survey estimates show that the median household income was $95,699 (with a margin of error of +/- $12,124) and the median family income w...
2018Culture
It is home to the headquarters of Drury Hotels, and was the home of Monsanto until its acquisition by Bayer in 2018.
2020History
=== 2020 census ===
The 2020 United States census counted 18,834 people, 8,230 households, and 4,817 families in Creve Coeur.